RNA Polymerase Holoenzyme-Open Promoter Complex

Nylon Model

RNA Polymerase Core Enzyme with Sigma removed

Nylon Model

RNA Polymerase Holoenzyme

Nylon Model

RNA Polymerase Holoenzyme: separated to expose active site and to remove nucleic acids/sigma factor

Nylon Model

RNA Polymerase Ternary Elongation Complex

RNA transcript colored red. Nylon Model

RNA Polymerase Ternary Elongation Complex

Active site amino acids (seven conserved residues, NADFDGD) shown with sidechains. Mg2+ ion colored purple. Nylon Model

RNA Polymerase Ternary Elongation Complex: model separated to expose active site

Nylon Model

RNA Polymerase Ternary Elongation Complex: Nucleic acids removed from RNAP core enzyme

Nylon Model

Prokaryotic RNA Polymerase Activation Complex

ZCorp plaster model. Part of beta subunit removed to expose transcription bubble.

Sigma factor (promoter recognition subunit) complexed with promoter DNA

ZCorp plaster model. Colors on sigma show various domains. Grey is part of core RNAP. Green on DNA are promoter regions.

Cyclic AMP Receptor Protein (CRP) or Catabolite Activator Protein (CAP)

Nylon model. Cyclic AMP colored Red. Dimer interacts with UP-element (region upstream of the promoter DNA) and plays a role in increasing transcription levels.

T7 phage RNA Polymerase elongation complex

Nylon model. Based on PDB ID: 1MSW.

T7 phage RNA Polymerase Initiation (Promoter) complex

ZCorp plaster model. Based on PDB ID: 1CEZ.

T7 phage RNA Polymerase elongation complex

ZCorp plaster model. Based on PDB ID: 1MSW.